C1orf50

Across TCGA patient cohorts, C1orf50 protein abundance is significantly associated with the RNA expression of many other genes, with 7,130 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1orf50-associated genes across cancer lineages are YBX1, PGK1, and EBNA1BP2. Each is linked with C1orf50 in more than 4 cancer types. Because this analysis shows association rather than direction, both C1orf50-to-partner and partner-to-C1orf50 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf50 versus YBX1 in BRCA, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf50→partner) and Y-score (partner→C1orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YBX1 →	+0.824	+0.320	<.001	<.001	3	5
UCEC	PGK1 →	+1.227	+0.339	<.001	<.001	3	4
UCEC	EBNA1BP2 →	+1.069	+0.278	<.001	<.001	3	4
BRCA	CAP1 →	+0.429	+0.224	.002	.003	3	4
UCEC	DPH2 →	+0.851	+0.308	<.001	.002	3	4
UCEC	MED8 →	+0.547	+0.292	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,130 associations by consensus.

C1orf50 vs YBX1 — BRCA

Explore this scatter interactively →