C1orf50

Across TCGA cell cohorts, C1orf50 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,739 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1orf50-associated GO terms across cancer lineages are RISC complex assembly, Regulation of macroautophagy, and Negative regulation of myoblast fusion. Each is linked with C1orf50 in more than 12 cancer types. Because this analysis shows association rather than direction, both C1orf50-to-partner and partner-to-C1orf50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RISC complex assembly grouped by C1orf50-low versus C1orf50-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf50→partner) and Y-score (partner→C1orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	RISC complex assembly →	+0.138	+0.664	<.001	<.001	3	13
URINARY_TRACT	Regulation of macroautophagy →	+0.042	+0.684	<.001	<.001	3	12
SKIN	Negative regulation of myoblast fusion →	+0.083	+0.573	.001	<.001	3	12
PANCREAS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.085	+0.644	<.001	<.001	3	12
BREAST	Cellular response to starvation →	+0.041	+0.472	.005	.003	2	12
STOMACH	Regulation of translational initiation →	+0.095	+0.826	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,739 associations by consensus.

RISC complex assembly by C1orf50 expression — STOMACH

Explore this box plot interactively →