C1orf43

Across TCGA patient cohorts, C1orf43 mutation is significantly associated with the RNA expression of many other genes, with 459 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf43-associated genes across cancer lineages are RNA5SP393, MTCO3P30, and MIR4692. Each is linked with C1orf43 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1orf43-to-partner and partner-to-C1orf43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP393 grouped by C1orf43-low versus C1orf43-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf43→partner) and Y-score (partner→C1orf43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP393 →	+0.227	+2.351	.008	.006	3	3
COAD	MTCO3P30 →	+0.099	+7.741	<.001	.009	3	2
BLCA	MIR4692 →	+0.881	+5.411	<.001	.005	3	2
SKCM	MIR4510 →	+0.354	+6.485	<.001	<.001	3	2
BLCA	RNU6-1115P →	+0.665	+5.411	<.001	.005	3	2
UCEC	RNU6-151P →	+0.372	+2.156	.008	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 459 associations by consensus.

RNA5SP393 by C1orf43 expression — UCEC

Explore this box plot interactively →