C1orf226

Across TCGA patient cohorts, C1orf226 protein abundance is significantly associated with the RNA expression of many other genes, with 6,582 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C1orf226-associated genes across cancer lineages are NOS1AP, SPATA46, and ABHD11. Each is linked with C1orf226 in more than 5 cancer types. Because this analysis shows association rather than direction, both C1orf226-to-partner and partner-to-C1orf226 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf226 versus NOS1AP in BRCA, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf226→partner) and Y-score (partner→C1orf226) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NOS1AP →	+1.281	+0.656	<.001	<.001	3	6
BRCA	SPATA46 →	+1.290	+0.650	<.001	<.001	3	4
HNSC	ABHD11 →	+1.632	+0.864	.001	<.001	3	3
BRCA	QSOX1 →	+0.709	+0.387	<.001	<.001	3	3
HNSC	KLHL12 →	+0.756	+0.432	.001	.008	2	4
BRCA	PARD6B →	+1.032	+0.494	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,582 associations by consensus.

C1orf226 vs NOS1AP — BRCA

Explore this scatter interactively →