C1orf194

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C1orf194 mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf194-associated genes across cancer lineages are NTAN1P1, IGHV1OR15-3, and COPS8P1. Each is linked with C1orf194 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf194-to-partner and partner-to-C1orf194 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NTAN1P1 grouped by C1orf194-low versus C1orf194-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf194→partner) and Y-score (partner→C1orf194) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNTAN1P1 →+0.111+3.937.004.00131
UCECIGHV1OR15-3 →+0.138+3.355.001.00231
UCECCOPS8P1 →+0.125+2.842<.001.00731
UCECMIR4727 →+0.396+3.551.001.00431
UCECMIR6085 →+0.537+3.221.001.00131
COADTBC1D26-AS1 →+0.213+4.209<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

NTAN1P1 by C1orf194 expression — UCEC

Box plot of NTAN1P1 in C1orf194-low vs C1orf194-high samples in UCEC.

Explore this box plot interactively →

Exploration