C1orf189

Across TCGA patient cohorts, C1orf189 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,311 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C1orf189-associated proteins across cancer lineages are SPATA18_S509, TPPP3, and RFX2_S171. Each is linked with C1orf189 in more than 4 cancer types. Because this analysis shows association rather than direction, both C1orf189-to-partner and partner-to-C1orf189 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf189 versus SPATA18_S509 in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf189→partner) and Y-score (partner→C1orf189) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPATA18_S509 →	+1.711	+0.863	<.001	<.001	3	5
UCEC	TPPP3 →	+1.806	+1.594	<.001	<.001	3	5
UCEC	RFX2_S171 →	+0.802	+1.144	<.001	<.001	3	5
UCEC	RPGR_S961 →	+0.674	+1.365	<.001	<.001	3	5
BRCA	DNALI1 →	+0.778	+0.782	.004	.003	3	5
UCEC	MDM1_T515 →	+1.028	+1.802	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,311 associations by consensus.

C1orf189 vs SPATA18_S509 — LSCC

Explore this scatter interactively →