Across TCGA patient cohorts, C1orf185 mutation is significantly associated with the RNA expression of many other genes, with 1,188 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf185-associated genes across cancer lineages are C2orf69P4, GCATP1, and HSPE1P19. Each is linked with C1orf185 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf185-to-partner and partner-to-C1orf185 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf185→partner) and Y-score (partner→C1orf185) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C2orf69P4 →	+0.084	+7.741	<.001	.009	3	1
UCEC	GCATP1 →	+0.409	+3.627	.001	.001	3	1
UCEC	HSPE1P19 →	+0.221	+2.719	<.001	.006	3	1
UCEC	POM121C →	+0.586	+3.212	<.001	.009	3	1
UCEC	DCP1A →	+0.781	+3.584	<.001	.003	3	1
UCEC	LINC02348 →	+0.587	+2.134	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,188 associations by consensus.

Exploration

C1orf185 survival (RNA) · tumor vs normal (RNA) · all C1orf185 data types