Across TCGA cell cohorts, C1orf185 RNA expression is significantly associated with the go_rna of many other GO terms, with 148 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible C1orf185-associated GO terms across cancer lineages are Synaptic vesicle lumen acidification, Regulation of MHC class II biosynthetic process, and Positive regulation of MHC class II biosynthetic process. Each is linked with C1orf185 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf185-to-partner and partner-to-C1orf185 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf185→partner) and Y-score (partner→C1orf185) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Synaptic vesicle lumen acidification →	+0.095	+0.085	<.001	.003	3	2
BLOOD_Lymphoma	Regulation of MHC class II biosynthetic process →	+0.117	+0.032	<.001	.001	3	2
BLOOD_Lymphoma	Positive regulation of MHC class II biosynthetic process →	+0.091	+0.029	.001	.003	3	2
BLOOD_Lymphoma	Regulation of nitric-oxide synthase activity →	-0.115	-0.023	.002	.004	3	2
CNS	Translesion synthesis →	+0.049	+0.069	.002	.003	3	2
LUNG_SCLC	Synaptic vesicle maturation →	+0.083	+0.065	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 148 associations by consensus.

Exploration

C1orf185 survival (RNA) · tumor vs normal (RNA) · all C1orf185 data types