Across TCGA patient cohorts, C1orf174 protein abundance is significantly associated with the RNA expression of many other genes, with 6,623 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf174-associated genes across cancer lineages are PANK4, POLR3H, and MRPL20. Each is linked with C1orf174 in more than 4 cancer types. Because this analysis shows association rather than direction, both C1orf174-to-partner and partner-to-C1orf174 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf174→partner) and Y-score (partner→C1orf174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PANK4 →	+0.821	+0.409	<.001	<.001	3	5
UCEC	POLR3H →	+0.696	+0.315	<.001	.002	3	4
UCEC	MRPL20 →	+0.657	+0.320	.001	<.001	3	4
UCEC	H2BC7 →	+1.107	+0.297	.003	.007	3	4
UCEC	SDHB →	+1.004	+0.434	<.001	<.001	3	4
UCEC	LMNB1 →	+1.006	+0.384	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,623 associations by consensus.

Exploration

C1orf174 survival (RNA) · tumor vs normal (RNA) · all C1orf174 data types