C1orf158

Across TCGA patient cohorts, C1orf158 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,113 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C1orf158-associated GO terms across cancer lineages are Organelle disassembly, Positive regulation of cilium assembly, and Epithelial cilium movement involved in determination of left/right asymmetry. Each is linked with C1orf158 in more than 17 cancer types. Because this analysis shows association rather than direction, both C1orf158-to-partner and partner-to-C1orf158 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle disassembly grouped by C1orf158-low versus C1orf158-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf158→partner) and Y-score (partner→C1orf158) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Organelle disassembly →	+0.072	+0.136	<.001	<.001	3	18
ESCA	Positive regulation of cilium assembly →	+0.070	+0.161	<.001	.005	3	16
UCEC	Epithelial cilium movement involved in determination of left/right asymmetry →	+0.103	+2.112	<.001	<.001	3	16
STAD	ATP biosynthetic process →	+0.084	+0.140	<.001	<.001	3	16
STAD	Proton motive force-driven ATP synthesis →	+0.091	+0.139	<.001	<.001	3	16
STAD	Cytoskeleton-dependent intracellular transport →	+0.059	+0.161	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,113 associations by consensus.

Organelle disassembly by C1orf158 expression — STAD

Explore this box plot interactively →