C1orf158

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C1orf158 protein abundance is significantly associated with the RNA expression of many other genes, with 892 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf158-associated genes across cancer lineages are DNAH7, CNGA4, and TTC29. Each is linked with C1orf158 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf158-to-partner and partner-to-C1orf158 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf158 versus DNAH7 in LSCC, with a Pearson correlation of 0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf158→partner) and Y-score (partner→C1orf158) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCDNAH7 →+1.424+1.300<.001.00732
LSCCCNGA4 →+1.709+1.998.002.00732
LSCCTTC29 →+1.412+1.300.006.00732
LSCCTCTE1 →+0.883+1.300.006.00732
LSCCDNAAF1 →+1.863+1.300<.001.00732
LSCCAK9 →+1.153+2.025<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 892 associations by consensus.

C1orf158 vs DNAH7 — LSCC

Per-sample scatter of C1orf158 vs DNAH7 in LSCC (Pearson r = 0.92).

Explore this scatter interactively →

Exploration