C1orf127

Across TCGA patient cohorts, C1orf127 protein abundance is significantly associated with the RNA expression of many other genes, with 102 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible C1orf127-associated genes across cancer lineages are AQP8, AIMP2, and PCDHB15. Each is linked with C1orf127 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf127-to-partner and partner-to-C1orf127 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf127 versus AQP8 in LUAD, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf127→partner) and Y-score (partner→C1orf127) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	AQP8 →	+0.107	+0.501	.002	.002	3	1
LUAD	AIMP2 →	-0.492	-0.571	.002	<.001	3	1
LUAD	PCDHB15 →	+0.636	+0.452	.002	.005	3	1
LUAD	SLC25A19 →	-0.555	-0.685	.004	.006	3	1
LUAD	SHC2 →	+0.956	+0.579	.001	<.001	3	1
LUAD	LYVE1 →	+0.580	+0.501	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 102 associations by consensus.

C1orf127 vs AQP8 — LUAD

Explore this scatter interactively →