C1orf127

Across TCGA patient cohorts, C1orf127 mutation is significantly associated with the RNA expression of many other genes, with 902 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf127-associated genes across cancer lineages are C9orf50, GMDS, and CXCL13. Each is linked with C1orf127 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1orf127-to-partner and partner-to-C1orf127 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf50 grouped by C1orf127-low versus C1orf127-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf127→partner) and Y-score (partner→C1orf127) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C9orf50 →	-0.530	-3.247	.001	<.001	3	3
SKCM	GMDS →	+0.318	+1.669	.008	.007	3	3
UCEC	CXCL13 →	+1.874	+2.584	<.001	.001	3	2
LUAD	REG1CP →	+0.011	+4.418	.006	.006	3	2
LUAD	LINC02238 →	+0.039	+4.590	<.001	.004	3	2
LUAD	EIF3EP2 →	+0.017	+3.330	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 902 associations by consensus.

C9orf50 by C1orf127 expression — UCEC

Explore this box plot interactively →