C1orf127

Across TCGA cell cohorts, C1orf127 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1orf127-associated genes across cancer lineages are TMEM239, TDRD15, and OR2F2. Each is linked with C1orf127 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf127-to-partner and partner-to-C1orf127 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM239 grouped by C1orf127-low versus C1orf127-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf127→partner) and Y-score (partner→C1orf127) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TMEM239 →	+0.126	+3.556	.003	.007	3	1
OESOPHAGUS	TDRD15 →	+0.006	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR2F2 →	+0.027	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR13C7 →	+0.037	+5.266	<.001	.001	3	1
BLOOD_Leukemia	CASQ2 →	+0.051	+2.926	<.001	.009	3	1
BLOOD_Leukemia	CPN1 →	+0.187	+4.083	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

TMEM239 by C1orf127 expression — SOFT_TISSUE

Explore this box plot interactively →