C1orf112

Across TCGA patient cohorts, C1orf112 protein abundance is significantly associated with the RNA expression of many other genes, with 6,922 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf112-associated genes across cancer lineages are STIL, SF3B4, and CENPM. Each is linked with C1orf112 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1orf112-to-partner and partner-to-C1orf112 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf112 versus STIL in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf112→partner) and Y-score (partner→C1orf112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STIL →	+1.040	+0.923	.001	.009	3	3
LSCC	SF3B4 →	+0.839	+0.686	<.001	<.001	3	3
LSCC	CENPM →	+0.723	+0.533	<.001	.001	3	2
LUAD	MYBL2 →	+1.815	+0.611	<.001	<.001	3	2
LSCC	E2F1 →	+1.275	+0.650	<.001	<.001	3	2
LUAD	FAM83D →	+1.252	+0.683	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,922 associations by consensus.

C1orf112 vs STIL — BRCA

Explore this scatter interactively →