C1orf105

Across TCGA patient cohorts, C1orf105 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,973 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1orf105-associated proteins across cancer lineages are LARP4_S722, LIMCH1_S377, and LTB4R_S320. Each is linked with C1orf105 in more than 3 cancer types. Because this analysis shows association rather than direction, both C1orf105-to-partner and partner-to-C1orf105 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf105 versus LARP4_S722 in HNSC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf105→partner) and Y-score (partner→C1orf105) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LARP4_S722 →	-0.271	-0.500	.003	<.001	3	3
HNSC	LIMCH1_S377 →	+1.004	+0.514	<.001	.002	3	3
COAD	LTB4R_S320 →	-0.794	-0.396	<.001	.005	3	3
GBM	MGAT1 →	-0.344	-0.510	<.001	<.001	3	3
GBM	MPO →	-0.886	-0.319	<.001	<.001	3	3
GBM	MYO1E →	-0.293	-0.386	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,973 associations by consensus.

C1orf105 vs LARP4_S722 — HNSC

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