C1orf105

Across TCGA cell cohorts, C1orf105 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,148 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C1orf105-associated GO terms across cancer lineages are Peripheral nervous system axon regeneration, Membrane bending, and Regulation of actin filament-based movement. Each is linked with C1orf105 in more than 5 cancer types. Because this analysis shows association rather than direction, both C1orf105-to-partner and partner-to-C1orf105 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peripheral nervous system axon regeneration grouped by C1orf105-low versus C1orf105-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf105→partner) and Y-score (partner→C1orf105) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Peripheral nervous system axon regeneration →	-0.381	-3.368	.002	<.001	3	5
PANCREAS	Membrane bending →	+0.145	+0.142	.001	.005	2	5
LUNG_NSCLC_LUAD	Regulation of actin filament-based movement →	+0.126	+0.294	<.001	.001	3	4
LUNG_NSCLC_LUAD	Negative regulation of protein polymerization →	+0.059	+0.201	.006	.004	3	4
LUNG_NSCLC_LUAD	Keratinocyte development →	-0.253	-0.159	<.001	.004	2	5
SOFT_TISSUE	Regulation of cytoplasmic mRNA processing body assembly →	+0.086	+2.801	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,148 associations by consensus.

Peripheral nervous system axon regeneration by C1orf105 expression — SOFT_TISSUE

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