C1QTNF9

Across TCGA pan-cancer cohorts, C1QTNF9 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated C1QTNF9 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C1QTNF9 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C1QTNF9 expression acts as an unfavorable survival marker.

HNSC, LUSC, and CHOL are the cancer types where C1QTNF9 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.176	0.685	.024	30	view →
LUSC	OS	Median	All	0.367	0.777	<.001	12	view →
CHOL	OS	Median	All	0.154	0.793	.004	9	view →
SKCM	DFS	Median	III,IV	0.016	0.648	<.001	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ESCA	OS	Median	II,III,IV	0.216	0.702	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

C1QTNF9–HNSC (OS)

Open the HNSC breakdown →