Across TCGA pan-cancer cohorts, C1QTNF8 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C1QTNF8 data layer compared with 18 for mass-spec protein.
The strongest signal is observed in mesothelioma (MESO), where higher C1QTNF8 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C1QTNF8 expression acts as an unfavorable survival marker.
MESO, SCLC, and SKCM are the cancer types where C1QTNF8 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.