Across TCGA pan-cancer cohorts, C1QTNF8 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of C1QTNF8’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where C1QTNF8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C1QTNF8 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

COAD, KIRP, and LUAD are the cancer types where C1QTNF8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C1QTNF8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.105	.006	4	view →
KIRP	All	All	+0.074	.007	4	view →
LUAD	Male	All	−0.063	.005	4	view →
LUSC	All	II,III,IV	−0.074	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: C1QTNF8 RNA expression & survival · all C1QTNF8 data types