Across TCGA cell cohorts, C1QTNF8 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C1QTNF8-associated genes across cancer lineages are DEFA4, GNG8, and MT1HL1. Each is linked with C1QTNF8 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF8-to-partner and partner-to-C1QTNF8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF8→partner) and Y-score (partner→C1QTNF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DEFA4 →	+0.053	+6.022	<.001	.001	3	1
LUNG_NSCLC_LUAD	GNG8 →	+0.268	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	MT1HL1 →	+0.173	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

C1QTNF8 survival (RNA) · tumor vs normal (RNA) · all C1QTNF8 data types