C1QTNF6

Across TCGA pan-cancer cohorts, C1QTNF6 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C1QTNF6 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher C1QTNF6 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated C1QTNF6 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

PDAC, HNSC, and UCEC are the cancer types where C1QTNF6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.285	0.486	.008	27	view →
HNSC	DFS	Quartile	All	0.361	0.798	.013	21	view →
UCEC	DFS	Median	All	0.986	0.824	.014	4	view →
LSCC	OS	Tertile	All	0.610	1.000	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

C1QTNF6–PDAC (DFS)

Open the PDAC breakdown →