C1QTNF6

Across TCGA pan-cancer cohorts, C1QTNF6 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of C1QTNF6’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where C1QTNF6 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types C1QTNF6 is over-expressed in tumor.

LSCC, LUAD, and PDAC are the cancer types where C1QTNF6 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C1QTNF6 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	Female	All	+2.059	<.001	9	view →
LUAD	All	III,IV	+2.022	<.001	8	view →
PDAC	Female	All	+1.850	<.001	7	view →
OV	All	All	+1.624	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

C1QTNF6–LSCC

Open the LSCC breakdown →