C1QTNF6

Across TCGA cell cohorts, C1QTNF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,558 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C1QTNF6-associated GO terms across cancer lineages are CD8-positive, alpha-beta T cell activation, Plasma membrane organization, and Regulation of pattern recognition receptor signaling pathway. Each is linked with C1QTNF6 in more than 10 cancer types. Because this analysis shows association rather than direction, both C1QTNF6-to-partner and partner-to-C1QTNF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8-positive, alpha-beta T cell activation grouped by C1QTNF6-low versus C1QTNF6-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF6→partner) and Y-score (partner→C1QTNF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CD8-positive, alpha-beta T cell activation →	+0.098	+0.985	<.001	<.001	3	11
URINARY_TRACT	Plasma membrane organization →	+0.115	+3.260	<.001	<.001	3	10
BONE	Regulation of pattern recognition receptor signaling pathway →	+0.070	+1.351	<.001	.004	3	10
STOMACH	Maintenance of protein localization in organelle →	+0.092	+1.667	<.001	.009	3	10
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.076	+2.597	.008	.009	3	10
PANCREAS	Modulation by symbiont of entry into host →	+0.130	+1.701	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,558 associations by consensus.

CD8-positive, alpha-beta T cell activation by C1QTNF6 expression — CNS

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