C1QTNF6

Across TCGA cell cohorts, C1QTNF6 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1QTNF6-associated genes across cancer lineages are UCN3, TFAP2D, and DEFA4. Each is linked with C1QTNF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF6-to-partner and partner-to-C1QTNF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UCN3 grouped by C1QTNF6-low versus C1QTNF6-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF6→partner) and Y-score (partner→C1QTNF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	UCN3 →	+0.055	+4.977	<.001	.007	3	1
SKIN	TFAP2D →	+0.189	+5.415	<.001	.004	3	1
LARGE_INTESTINE	DEFA4 →	+0.040	+5.022	<.001	.002	3	1
LARGE_INTESTINE	CCDC172 →	+0.004	+4.415	<.001	.007	3	1
BLOOD_Leukemia	OR1G1 →	+0.049	+4.705	<.001	.003	3	1
BLOOD_Leukemia	LYZL6 →	+0.029	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

UCN3 by C1QTNF6 expression — SKIN

Explore this box plot interactively →