C1QTNF4

Across TCGA patient cohorts, C1QTNF4 mutation is significantly associated with the RNA expression of many other genes, with 95 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1QTNF4-associated genes across cancer lineages are MIR1289-2, TRAJ52, and MIR6780A. Each is linked with C1QTNF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF4-to-partner and partner-to-C1QTNF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1289-2 grouped by C1QTNF4-low versus C1QTNF4-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF4→partner) and Y-score (partner→C1QTNF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR1289-2 →	+0.365	+6.111	<.001	.002	3	2
COAD	TRAJ52 →	+0.859	+3.754	<.001	.008	3	2
UCEC	MIR6780A →	+0.470	+2.801	<.001	.005	3	1
HNSC	TAS2R16 →	+0.046	+5.505	<.001	.004	3	1
HNSC	OR51T1 →	+0.066	+5.505	<.001	.004	3	1
HNSC	OR4F15 →	+0.033	+5.303	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 95 associations by consensus.

MIR1289-2 by C1QTNF4 expression — HNSC

Explore this box plot interactively →