C1QTNF3

Across TCGA patient cohorts, C1QTNF3 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1QTNF3-associated genes across cancer lineages are eIF4G, Notch1, and PCNA. Each is linked with C1QTNF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF3-to-partner and partner-to-C1QTNF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4G grouped by C1QTNF3-low versus C1QTNF3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF3→partner) and Y-score (partner→C1QTNF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4G →	+0.316	+2.321	.042	.035	3	1
UCEC	Notch1 →	+0.288	+3.179	<.001	.010	3	1
UCEC	PCNA →	+0.272	+2.321	.012	.035	3	1
UCEC	PDCD4 →	-0.557	-2.990	.018	.036	3	1
UCEC	AMPK_alpha →	-0.212	-3.169	.026	.019	3	1
UCEC	PKC-delta_pS664 →	-0.155	-3.160	.010	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

eIF4G by C1QTNF3 expression — UCEC

Explore this box plot interactively →