C1QTNF3

Across TCGA pan-cancer cohorts, C1QTNF3 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated C1QTNF3 data layer compared with 3 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher C1QTNF3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C1QTNF3 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LAML show a favorable association.

KICH, ACC, and OV are the cancer types where C1QTNF3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Quartile	II,III,IV	0.513	1.000	.002	95	view →
ACC	DFS	Tertile	All	0.347	0.830	<.001	83	view →
OV	DFS	Quartile	All	0.468	0.608	.003	48	view →
KIRC	OS	Median	II,III,IV	0.646	0.456	.004	43	view →
LAML	DFS	Tertile	All	0.583	0.290	<.001	42	view →
KIRP	DFS	Median	IV	0.038	0.594	.002	39	view →
SKCM	OS	Tertile	All	0.393	0.253	.004	36	view →
LUAD	OS	Median	II,III,IV	0.777	0.634	<.001	35	view →
THYM	OS	Median	All	1.000	0.698	<.001	27	view →
THCA	DFS	Median	II,III,IV	0.639	0.905	.001	26	view →
UCS	DFS	Quartile	III,IV	0.754	0.262	.009	18	view →
UVM	OS	Median	III,IV	0.281	1.000	.003	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

C1QTNF3–KICH (DFS)

Open the KICH breakdown →