C1QTNF3-AMACR

Across TCGA pan-cancer cohorts, C1QTNF3-AMACR RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated C1QTNF3-AMACR data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C1QTNF3-AMACR RNA is associated with better overall survival. In most high-consensus cancer types, elevated C1QTNF3-AMACR expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, HNSC, and UCEC are the cancer types where C1QTNF3-AMACR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	II,III,IV	0.618	0.314	<.001	85	view →
HNSC	DFS	Tertile	IV	0.768	0.553	<.001	69	view →
UCEC	DFS	Quartile	All	0.443	0.771	<.001	64	view →
KIRP	DFS	Median	II,III,IV	0.891	0.251	.001	55	view →
UVM	OS	Median	II,III,IV	0.842	0.582	.019	34	view →
SKCM	DFS	Median	All	0.690	0.534	<.001	26	view →
BRCA	DFS	Median	All	0.452	0.586	.007	19	view →
DLBC	OS	Median	All	0.599	1.000	.005	19	view →
GBM	OS	Quartile	All	0.648	0.343	.017	18	view →
ESCA	OS	Quartile	III,IV	0.789	0.400	.009	17	view →
LGG	OS	Median	All	0.855	0.951	<.001	13	view →
THYM	DFS	Tertile	II,III,IV	0.886	0.579	.008	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

C1QTNF3-AMACR–LUAD (OS)

Open the LUAD breakdown →