C1QTNF3-AMACR

Across TCGA pan-cancer cohorts, C1QTNF3-AMACR RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of C1QTNF3-AMACR’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where C1QTNF3-AMACR RNA is repressed in tumor relative to normal tissue. In most cancer types C1QTNF3-AMACR is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, KIRC, and LIHC are the cancer types where C1QTNF3-AMACR tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C1QTNF3-AMACR RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.058	<.001	10	view →
KIRC	All	All	+0.022	.002	8	view →
LIHC	Male	All	+0.031	<.001	7	view →
THCA	All	All	−0.021	.006	7	view →
LUSC	All	All	+0.086	<.001	5	view →
BLCA	Male	IV	+0.072	.004	4	view →
STAD	Female	All	+0.067	.017	4	view →
HNSC	All	All	+0.027	.030	4	view →
UCEC	All	IV	−0.110	.008	2	view →
CHOL	All	All	+0.082	.011	2	view →
LUAD	All	All	+0.046	.016	2	view →
PRAD	All	All	+0.032	.012	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

C1QTNF3-AMACR–KICH

Open the KICH breakdown →