Across TCGA pan-cancer cohorts, C1QTNF12 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated C1QTNF12 data layer compared with 3 for mutation status.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher C1QTNF12 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C1QTNF12 expression acts as an unfavorable survival marker, although some lineages such as HNSC and THYM show a favorable association.
ACC, UCEC, and LIHC are the cancer types where C1QTNF12 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.