C1QTNF12

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, C1QTNF12 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C1QTNF12 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher C1QTNF12 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C1QTNF12 expression acts as an unfavorable survival marker.

COAD, PRAD, and SCLC are the cancer types where C1QTNF12 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSMedianIII,IV0.1330.783<.00112view →
PRADDFSMedianAll0.0850.774<.0016view →
SCLCOSMedianAll0.2190.706.0116view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration