C1QL2

Across TCGA cell cohorts, C1QL2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1QL2-associated genes across cancer lineages are C1QTNF7, GSG1L2, and GNGT1. Each is linked with C1QL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QL2-to-partner and partner-to-C1QL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QTNF7 grouped by C1QL2-low versus C1QL2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QL2→partner) and Y-score (partner→C1QL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C1QTNF7 →	+0.066	+4.108	.009	.008	3	1
LARGE_INTESTINE	GSG1L2 →	+0.013	+4.022	<.001	.006	3	1
BLOOD_Leukemia	GNGT1 →	+0.055	+3.551	<.001	.009	3	1
BLOOD_Leukemia	OR10R2 →	+1.568	+3.551	<.001	.009	3	1
BLOOD_Leukemia	KRTAP6-3 →	+0.150	+4.984	<.001	.002	3	1
LARGE_INTESTINE	RSC1A1 →	+1.023	+3.519	.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

C1QTNF7 by C1QL2 expression — LARGE_INTESTINE

Explore this box plot interactively →