C1QL1

Across TCGA pan-cancer cohorts, C1QL1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated C1QL1 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C1QL1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C1QL1 expression acts as an unfavorable survival marker.

HNSC, STAD, and BLCA are the cancer types where C1QL1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	IV	0.021	0.709	<.001	36	view →
STAD	OS	Median	All	0.001	0.667	<.001	30	view →
BLCA	OS	Median	III,IV	0.051	0.684	<.001	24	view →
SKCM	OS	Median	All	0.230	0.781	.004	16	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
COAD	DFS	Median	All	0.229	0.690	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

C1QL1–HNSC (OS)

Open the HNSC breakdown →