C1QL1

Across TCGA cell cohorts, C1QL1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1QL1-associated genes across cancer lineages are BANF2, REG3G, and PPDPFL. Each is linked with C1QL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QL1-to-partner and partner-to-C1QL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BANF2 grouped by C1QL1-low versus C1QL1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QL1→partner) and Y-score (partner→C1QL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	BANF2 →	+0.096	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	REG3G →	+0.026	+4.867	.004	.009	3	1
LARGE_INTESTINE	PPDPFL →	+0.048	+4.217	<.001	.001	3	1
LARGE_INTESTINE	OR52K1 →	+0.015	+4.217	<.001	.001	3	1
LUNG_NSCLC_LUAD	NPVF →	+0.014	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR1E2 →	+0.016	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

BANF2 by C1QL1 expression — BLOOD_Lymphoma

Explore this box plot interactively →