C1QBP

Across TCGA patient cohorts, C1QBP protein abundance is significantly associated with the RNA expression of many other genes, with 14,125 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1QBP-associated genes across cancer lineages are NUP88, CNRIP1, and CLEC1A. Each is linked with C1QBP in more than 5 cancer types. Because this analysis shows association rather than direction, both C1QBP-to-partner and partner-to-C1QBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1QBP versus NUP88 in OV, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QBP→partner) and Y-score (partner→C1QBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NUP88 →	+0.671	+0.819	<.001	<.001	3	6
OV	CNRIP1 →	-0.911	-0.838	<.001	<.001	3	6
UCEC	CLEC1A →	-0.648	-0.347	<.001	.001	3	6
LSCC	CASS4 →	-0.718	-0.513	<.001	<.001	3	6
OV	SELL →	-1.282	-0.582	.001	.004	3	6
OV	JAM2 →	-0.892	-0.710	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,125 associations by consensus.

C1QBP vs NUP88 — OV

Explore this scatter interactively →