C1GALT1C1

Across TCGA cell cohorts, C1GALT1C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,712 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C1GALT1C1-associated GO terms across cancer lineages are Protein targeting to lysosome involved in chaperone-mediated autophagy, Protein targeting to vacuole involved in autophagy, and Protein demannosylation. Each is linked with C1GALT1C1 in more than 12 cancer types. Because this analysis shows association rather than direction, both C1GALT1C1-to-partner and partner-to-C1GALT1C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to lysosome involved in chaperone-mediated autophagy grouped by C1GALT1C1-low versus C1GALT1C1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1GALT1C1→partner) and Y-score (partner→C1GALT1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.173	+0.885	<.001	.003	3	13
SOFT_TISSUE	Protein targeting to vacuole involved in autophagy →	+0.153	+0.599	<.001	<.001	3	10
CNS	Protein demannosylation →	+0.088	+0.758	<.001	.003	3	9
CNS	Protein alpha-1,2-demannosylation →	+0.088	+0.758	<.001	.003	3	9
BLOOD_Myeloma	Endoplasmic reticulum organization →	+0.080	+0.960	.001	<.001	3	9
LIVER	Oligosaccharide catabolic process →	+0.140	+0.917	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,712 associations by consensus.

Protein targeting to lysosome involved in chaperone-mediated autophagy by C1GALT1C1 expression — PANCREAS

Explore this box plot interactively →