C1GALT1C1

Across TCGA cell cohorts, C1GALT1C1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1GALT1C1-associated genes across cancer lineages are H1-6, IQCF6, and ADAM7. Each is linked with C1GALT1C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1GALT1C1-to-partner and partner-to-C1GALT1C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H1-6 grouped by C1GALT1C1-low versus C1GALT1C1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1GALT1C1→partner) and Y-score (partner→C1GALT1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	H1-6 →	+0.126	+3.509	<.001	.008	3	1
LARGE_INTESTINE	IQCF6 →	+0.228	+3.882	<.001	.001	3	1
LARGE_INTESTINE	ADAM7 →	+0.004	+3.345	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

H1-6 by C1GALT1C1 expression — LARGE_INTESTINE

Explore this box plot interactively →