C19orf81

Across TCGA patient cohorts, C19orf81 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,130 significant associations in total. LGG shows the largest number of these associations.

The most reproducible C19orf81-associated GO terms across cancer lineages are tRNA thio-modification, ATP biosynthetic process, and Proton motive force-driven ATP synthesis. Each is linked with C19orf81 in more than 22 cancer types. Because this analysis shows association rather than direction, both C19orf81-to-partner and partner-to-C19orf81 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA thio-modification grouped by C19orf81-low versus C19orf81-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf81→partner) and Y-score (partner→C19orf81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	tRNA thio-modification →	+0.077	+1.824	<.001	<.001	3	21
STAD	ATP biosynthetic process →	+0.044	+0.347	<.001	.001	1	23
STAD	Proton motive force-driven ATP synthesis →	+0.045	+0.283	<.001	.009	1	21
STAD	Oxidative phosphorylation →	+0.042	+0.315	<.001	.003	2	20
STAD	NADH dehydrogenase complex assembly →	+0.046	+0.479	.004	.001	2	19
MESO	Medium-chain fatty acid catabolic process →	-0.072	-1.181	.001	.001	1	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,130 associations by consensus.

tRNA thio-modification by C19orf81 expression — UCS

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