C19orf81

Across TCGA pan-cancer cohorts, C19orf81 RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated C19orf81 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher C19orf81 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C19orf81 expression acts as an unfavorable survival marker, although some lineages such as UVM and CESC show a favorable association.

COAD, UVM, and KIRC are the cancer types where C19orf81 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	IV	0.315	0.759	<.001	125	view →
UVM	DFS	Tertile	All	0.793	0.419	<.001	95	view →
KIRC	DFS	Median	All	0.546	0.710	<.001	71	view →
UCS	DFS	Median	IV	0.367	0.952	.001	36	view →
CESC	DFS	Median	IV	0.759	0.274	.001	36	view →
ESCA	DFS	Median	II,III,IV	0.350	0.595	<.001	27	view →
GBM	OS	Tertile	All	0.285	0.614	<.001	21	view →
PAAD	OS	Quartile	All	0.625	0.278	.004	21	view →
LUSC	OS	Tertile	III,IV	0.267	0.547	.009	19	view →
LAML	DFS	Tertile	All	0.543	0.243	.002	18	view →
BRCA	DFS	Quartile	III,IV	0.781	0.906	.005	17	view →
OV	OS	Tertile	All	0.415	0.325	.028	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

C19orf81–COAD (DFS)

Open the COAD breakdown →