C19orf57

Across TCGA patient cohorts, C19orf57 protein abundance is significantly associated with the RNA expression of many other genes, with 996 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C19orf57-associated genes across cancer lineages are CCDC134, CENPM, and MCM5. Each is linked with C19orf57 in more than 1 cancer types. Because this analysis shows association rather than direction, both C19orf57-to-partner and partner-to-C19orf57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C19orf57 versus CCDC134 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf57→partner) and Y-score (partner→C19orf57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCDC134 →	+0.443	+0.632	.003	.003	3	1
BRCA	CENPM →	+0.823	+0.579	.002	.008	3	1
BRCA	MCM5 →	+0.916	+0.953	.002	.007	3	1
BRCA	E2F1 →	+1.280	+1.061	.003	.004	3	1
BRCA	METTL4 →	+0.589	+1.035	.004	.002	3	1
BRCA	CEP76 →	+0.372	+0.639	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 996 associations by consensus.

C19orf57 vs CCDC134 — BRCA

Explore this scatter interactively →