C19orf57

Across TCGA cell cohorts, C19orf57 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,575 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C19orf57-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Regulation of DNA repair, and Mitotic chromosome condensation. Each is linked with C19orf57 in more than 9 cancer types. Because this analysis shows association rather than direction, both C19orf57-to-partner and partner-to-C19orf57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by C19orf57-low versus C19orf57-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf57→partner) and Y-score (partner→C19orf57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.168	+1.107	.002	.003	3	10
SOFT_TISSUE	Regulation of DNA repair →	+0.046	+1.089	<.001	<.001	3	9
BONE	Mitotic chromosome condensation →	+0.148	+0.836	.008	.007	3	9
LUNG_SCLC	Positive regulation of stem cell population maintenance →	+0.107	+1.396	<.001	<.001	3	9
LUNG_SCLC	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.117	+1.281	.001	.001	3	9
SOFT_TISSUE	Mitotic spindle midzone assembly →	+0.240	+1.225	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,575 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by C19orf57 expression — BONE

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