C19orf48

Across TCGA cell cohorts, C19orf48 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,360 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C19orf48-associated GO terms across cancer lineages are DNA replication checkpoint signaling, DNA strand elongation involved in DNA replication, and Leading strand elongation. Each is linked with C19orf48 in more than 17 cancer types. Because this analysis shows association rather than direction, both C19orf48-to-partner and partner-to-C19orf48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication checkpoint signaling grouped by C19orf48-low versus C19orf48-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf48→partner) and Y-score (partner→C19orf48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication checkpoint signaling →	+0.274	+1.575	<.001	<.001	3	18
BONE	DNA strand elongation involved in DNA replication →	+0.223	+1.417	<.001	<.001	3	17
BONE	Leading strand elongation →	+0.219	+1.340	<.001	<.001	3	17
BONE	Nuclear DNA replication →	+0.226	+1.482	<.001	<.001	3	16
BONE	U4 snRNA 3'-end processing →	+0.158	+1.004	.001	.004	3	16
BONE	Mitotic DNA replication →	+0.256	+1.641	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,360 associations by consensus.

DNA replication checkpoint signaling by C19orf48 expression — BONE

Explore this box plot interactively →