C19orf47

Across TCGA patient cohorts, C19orf47 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C19orf47-associated genes across cancer lineages are MEK1, PCNA, and TFRC. Each is linked with C19orf47 in more than 1 cancer types. Because this analysis shows association rather than direction, both C19orf47-to-partner and partner-to-C19orf47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by C19orf47-low versus C19orf47-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf47→partner) and Y-score (partner→C19orf47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.314	+2.087	.025	.005	3	2
UCEC	PCNA →	+0.185	+2.321	.025	.033	3	2
UCEC	TFRC →	+0.464	+2.000	.022	.030	3	2
UCEC	Cyclin-B1 →	+0.483	+3.169	.025	.018	3	2
UCEC	eIF4E →	+0.161	+1.678	.047	.023	3	1
UCEC	Lck →	+0.184	+1.678	.016	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

MEK1 by C19orf47 expression — UCEC

Explore this box plot interactively →