C19orf18

Across TCGA patient cohorts, C19orf18 mutation is significantly associated with the RNA expression of many other genes, with 1,182 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C19orf18-associated genes across cancer lineages are NF1P10, CLPB, and MAIP1. Each is linked with C19orf18 in more than 2 cancer types. Because this analysis shows association rather than direction, both C19orf18-to-partner and partner-to-C19orf18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NF1P10 grouped by C19orf18-low versus C19orf18-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf18→partner) and Y-score (partner→C19orf18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NF1P10 →	+0.221	+3.875	.001	<.001	3	3
SKCM	CLPB →	+0.732	+3.214	.002	.009	3	2
UCEC	MAIP1 →	+0.563	+3.595	.009	.001	3	2
UCEC	MPC1 →	+0.556	+3.202	.006	.009	3	2
UCEC	GOLGA3 →	+0.534	+3.606	<.001	.001	3	2
SKCM	NAGPA →	+0.455	+3.214	.009	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,182 associations by consensus.

NF1P10 by C19orf18 expression — SKCM

Explore this box plot interactively →