C19orf18

Across TCGA cell cohorts, C19orf18 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,026 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C19orf18-associated GO terms across cancer lineages are COPII vesicle coating, Vesicle targeting, rough ER to cis-Golgi, and Vesicle coating. Each is linked with C19orf18 in more than 8 cancer types. Because this analysis shows association rather than direction, both C19orf18-to-partner and partner-to-C19orf18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII vesicle coating grouped by C19orf18-low versus C19orf18-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf18→partner) and Y-score (partner→C19orf18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	COPII vesicle coating →	+0.087	+0.367	.004	<.001	3	9
LUNG_SCLC	Vesicle targeting, rough ER to cis-Golgi →	+0.088	+0.384	.001	<.001	3	7
SKIN	Vesicle coating →	+0.052	+0.133	.001	<.001	3	7
SOFT_TISSUE	Regulation of stem cell differentiation →	+0.072	+0.474	<.001	<.001	3	7
CNS	Aromatic amino acid metabolic process →	-0.126	-0.258	<.001	<.001	3	7
SKIN	Maintenance of sister chromatid cohesion →	-0.094	-0.169	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,026 associations by consensus.

COPII vesicle coating by C19orf18 expression — LUNG_SCLC

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