Across TCGA cell cohorts, C18orf63 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C18orf63-associated genes across cancer lineages are SPINK9, UCP1, and LRRC9. Each is linked with C18orf63 in more than 1 cancer types. Because this analysis shows association rather than direction, both C18orf63-to-partner and partner-to-C18orf63 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf63→partner) and Y-score (partner→C18orf63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SPINK9 →	+0.351	+3.793	<.001	.007	3	2
SKIN	UCP1 →	+0.149	+3.684	.001	.009	3	1
SKIN	LRRC9 →	+0.151	+4.347	<.001	.001	3	1
SKIN	ACP4 →	+0.015	+4.196	.002	.002	3	1
SKIN	DEUP1 →	+0.529	+3.793	<.001	.007	3	1
SKIN	MMP26 →	+0.016	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

C18orf63 survival (RNA) · tumor vs normal (RNA) · all C18orf63 data types