C18orf54

Across TCGA patient cohorts, C18orf54 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,299 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C18orf54-associated proteins across cancer lineages are MCM5, RRM2, and PRIM2. Each is linked with C18orf54 in more than 8 cancer types. Because this analysis shows association rather than direction, both C18orf54-to-partner and partner-to-C18orf54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C18orf54 versus MCM5 in LUAD, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf54→partner) and Y-score (partner→C18orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MCM5 →	+0.737	+0.573	<.001	<.001	3	9
LUAD	RRM2 →	+0.716	+0.522	<.001	<.001	3	8
GBM	PRIM2 →	+0.463	+0.732	.004	<.001	3	8
GBM	SMC4 →	+0.597	+0.603	<.001	<.001	3	8
GBM	STMN1 →	+0.715	+0.740	<.001	<.001	3	8
LUAD	MCM2 →	+0.710	+0.569	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,299 associations by consensus.

C18orf54 vs MCM5 — LUAD

Explore this scatter interactively →