C18orf32

Across TCGA patient cohorts, C18orf32 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C18orf32-associated genes across cancer lineages are Myosin-IIa_pS1943, Notch1, and PDCD4. Each is linked with C18orf32 in more than 1 cancer types. Because this analysis shows association rather than direction, both C18orf32-to-partner and partner-to-C18orf32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa_pS1943 grouped by C18orf32-low versus C18orf32-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf32→partner) and Y-score (partner→C18orf32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Myosin-IIa_pS1943 →	+0.240	+2.700	.004	.006	3	1
UCEC	Notch1 →	+0.211	+3.000	<.001	.001	3	1
UCEC	PDCD4 →	-0.513	-1.807	.008	.027	3	1
UCEC	Rab25 →	-0.544	-2.906	<.001	.001	3	1
UCEC	Annexin-1 →	+0.682	+3.604	.001	.001	3	1
UCEC	SF2 →	-0.116	-1.794	.010	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Myosin-IIa_pS1943 by C18orf32 expression — UCEC

Explore this box plot interactively →