Across TCGA patient cohorts, C17orf99 mutation is significantly associated with the RNA expression of many other genes, with 1,683 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf99-associated genes across cancer lineages are OFD1P16Y, DUX4L28, and PGAP2. Each is linked with C17orf99 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf99-to-partner and partner-to-C17orf99 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf99→partner) and Y-score (partner→C17orf99) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OFD1P16Y →	+0.103	+8.057	<.001	.005	3	1
BRCA	DUX4L28 →	+0.096	+8.057	<.001	.005	3	1
UCEC	PGAP2 →	+0.450	+3.823	.003	<.001	3	1
UCEC	CELF1 →	+0.416	+2.906	.006	.002	3	1
UCEC	COX15 →	+0.519	+3.592	<.001	.001	3	1
UCEC	SESN3 →	+1.094	+2.928	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,683 associations by consensus.

Exploration

C17orf99 survival (RNA) · tumor vs normal (RNA) · all C17orf99 data types